Endocrine Abstracts

According to the 4th edition of the WHO classification of endocrine organ tumors (2017), all pheochromocytomas are classified as malignant tumors (ICD-O code 8700/3). However, in the literature there are no unambiguous data on the significance of clinical and laboratory predictors of the aggressiveness of pheochromocytoma. The aim of the study was to verify possible predictors of pheo-progression using clinical data, the results of laboratory and instrumental examination (incl...

Adrenocortical cancer (ACC) is a tumor of the adrenal cortex, clinical manifestations, recurrence, and progression potential are determined by its biological characteristics. Morphological diagnosis of tumors of the adrenal glands in some cases presents significant difficulties. According to the WHO classification of tumors of the endocrine organs (4th revision, 2017), in addition to the classical one, myxoid, sarcomatoid and oncocytic histological variants of ACC are distingu...

Neuroendocrine neoplasias (NENs) are a heterogeneous group of tumors that differ in appearance, growth patterns, and clinical symptoms and develop from neuroendocrine cells and, accordingly, unusually similar cytological characteristics. Pheochromocytoma is considered as not epithelial type of NENs. We would like to present a clinical case of pheochromocytoma with difficulties in laboratory diagnosis and morphological verification. Female patient P., 60 years old, for 10 years...